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Ethylphenidate is a synthetic molecule of the substituted phenethylamine class. It contains a phenethylamine core featuring a phenyl ring bound to an amino -NH2 group through an ethyl chain.Buy Ethylphenidate Powder Online
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Ethylphenidate is a synthetic molecule of the substituted phenethylamine class. It contains a phenethylamine core featuring a phenyl ring bound to an amino -NH2 group through an ethyl chain.Buy Ethylphenidate Powder Online It is structurally similar to amphetamine, featuring a substitution at Rα which is incorporated into a piperdine ring ending at the terminal amine of the phenethylamine chain. Additionally, it contains an ethyl acetate bound to R2 or its structure. Ethylphenidate is structurally differed to methylphenidate by elongation of the carbon chain. Ethyl- regards the side chain of two carbon atoms, phen- indicates the phenyl ring, id- is contracted from a piperidine ring, and -ate indicates the acetate group containing the oxygens. Ethylphenidate is a chiral compound, presumably produced as a racemic mixture.Contact us for more details.Buy Ethylphenidate Powder Online.Ethylphenidate (EPH) is a psychostimulant and a close analog of methylphenidate.Ethylphenidate acts as both a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters in the brain, by binding to, and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft.However, considering the close similarities between ethylphenidate and methylphenidate and the fact that methylphenidate, like cocaine, actually does not primarily act as a “classical” reuptake inhibitor, but rather as an “inverse agonist at the DAT” (also called a “negative allosteric modulator at the DAT”),it is at least very likely that ethylphenidate also primarily acts as an inverse DAT agonist instead of (or at least only secondarily) as a classical reuptake inhibitor (which could be called a “competitive antagonist at the DAT” using a similar terminology as “negative allosteric modulator at the DAT”, which per definition means that its mechanism is non-competitive).There have been anecdotal reports of a perforated septum resulting from even just a few uses of ethylphenidate by insufflation (snorting). Some users also report the drug is extremely painful to insufflate.Ethylphenidate metabolizes into methylphenidate and ritalinic acid.Tiny amounts of ethylphenidate can Buy Ethylphenidate Powder Online be formed in vivo when alcohol (also known formally as ethanol) and methylphenidate are coingested, via hepatic transesterification.Ethylphenidate formation appears to be more common when large quantities of methylphenidate and alcohol are consumed at the same time, such as in non-medical use or overdose scenarios.However, the transesterfication process of methylphenidate to ethylphenidate, as tested in mice liver, was dominant in the inactive (−)-enantiomer but showed a prolonged and increased maximal plasma concentration of the active (+)-enantiomer of methylphenidate.Additionally, only a few percent of the consumed methylphenidate is converted to ethylphenidate.This carboxylesterase-dependent transesterification process is also known to occur when cocaine and alcohol are consumed together, forming cocaethylene.All available data on ethylphenidate’s pharmacokinetics are drawn from studies conducted on rodents. Ethylphenidate is more selective to the dopamine transporter (DAT) than methylphenidate, having approximately the same efficacy as the parent compound,but has significantly less activity on the norepinephrine transporter (NET).Its dopaminergic pharmacodynamic profile is nearly identical to methylphenidate, and is primarily responsible for its euphoric and reinforcing effects.The eudysmic ratio for ethylphenidate is superior to that of methylphenidate.[not in citation given.The following is ethylphenidate’s binding profile in the mouse, alongside methylphenidate’s. Figures for both the racemic and the dextrorotary enantiomers are given:Ethylphenidate is not controlled internationally; see Convention on Psychotropic Substances.Buy Ethylphenidate Powder Online
Ethylphenidate is not controlled in the Netherlands, as the Opium Law does not cover it, nor is there any law covering analogs of controlled drugs (methylphenidate is covered). At the 16th of March 2017 the decision was made to start including Ethylphenidate in the Opium Law in the near future.
Ethylphenidate is not explicitly controlled in US but it could possibly be considered an analog of a Schedule II substance (methylphenidate) under the Federal Analog Act if sold for human consumption.
Ethylphenidate is illegal in Sweden as of 15 December 2012.Buy Ethylphenidate Powder Online
Ethylphenidate is illegal to manufacture, distribute or import in the UK, as of 10 April 2015 it has been placed under a Temporary Class Drug Order which automatically places it in a Class-B-like category.Though ordinarily the TCDO would only last 1 year, the ACMD reported that since its invocation prevalence of MPA had significantly decreased, and that it had been challenging to collect information about the drug. As a result of this, they requested that the TCDO be extended a further year from 26 June 2016.
Ethylphenidate is illegal in Jersey under the Misuse of Drugs (Jersey) Law 1978.
Australian state and federal legislation contains provisions that mean that analogues of controlled drugs are also covered by the legislation. Ethylphenidate would be an analogue of methylphenidate under this legislation.
Ethylphenidate is controlled in Canada under the Controlled Drugs and Substances Act under Schedule III as of 05.05.2017.Buy Ethylphenidate Powder Online
Ethylphenidate is illegal in Germany as of 05.07.2013
Ethylphenidate is illegal in Austria by the “Neue Psychoaktive Substanzen Gesetz” (=new psychoactive substances act) NPSG since 1 January 2012
Ethylphenidate is illegal in Denmark as of 1 February 2013.Ethylphenidate is illegal in Poland by “the Act on Counteracting Drug Addiction” since 1 July 2015 It is illegal in Lithuania to use, buy, possess, transport, sell or import Ethylphenidate from 2015 As of October 2015 Ethylphenidate is a controlled substance in China.Buy Ethylphenidate Powder Online
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